ERCC2(p.D312N)点突变HAP1细胞
货号:
EDC03290
物种:
人
细胞名称:
HAP1
基因名称:
ERCC2
基因ID:
2068
ERCC2(p.D312N)点突变HAP1细胞基于新开发的Bingo™平台,该平台采用优化升级版的Prime Editing (PE)基因点突变系统——目前最高效、最安全的技术。该平台可以实现精准、高效的基因点突变,从而获得高活性和稳定的细胞系。艾迪基因拥有大量的PE点突变细胞库存,能够高效、及时地提供高质量的产品。
| 货号 | EDC03290 |
|---|---|
| 产品名称 | ERCC2(p.D312N)点突变HAP1细胞 |
| 物种 | 人 |
| 细胞 | HAP1 |
| 突变位点 | p.D312N |
| 细胞别名 | HAP-1 |
| 基因 | ERCC2 |
| 基因ID | |
| 摘要 |
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
|
| 细胞形态 | 贴壁生长 |
| 传代比率 | 1:8~1:10 |
| 完全培养基 | IMDM+10%FBS |
| 冻存培养基 | 90%FBS+10%DMSO |
* 仅供科研使用,不适用于人体或动物,包括临床、治疗或诊断用途。
* 研究用途免责声明:本内容基于公开的研究数据、生物信息学资源及计算分析生成,仅供研究参考。