LRP1基因过表达Jurkat E6.1稳转细胞
货号:
EDC01588
物种:
人
细胞名称:
Jurkat E6.1
基因名称:
LRP1
基因ID:
4035
规格:
1×10⁶cells
艾迪基因基于自身成熟的基因编辑平台，通过慢病毒或转座子递送系统，将LRP1基因整合至Jurkat E6.1细胞的基因组中，然后经过真核抗性标记筛选出阳性细胞池，再使用3D单细胞打印技术挑选单克隆细胞，最后经过表达水平验证，检测合格后对细胞进行扩增和冻存。
| 货号 | EDC01588 |
|---|---|
| 产品名称 | LRP1基因过表达Jurkat E6.1稳转细胞 |
| 细胞 | Jurkat E6.1 |
| Cellosaurus ID | CVCL_0367 |
| 基因 | LRP1 |
| 基因ID | |
| 摘要 |
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
|
| 细胞形态 | 悬浮生长 |
| 传代比率 | / |
| 完全培养基 | RPMI-1640 + 10% FBS |
| 冻存培养基 | 95% 完全培养基 + 5% DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
| Loci | 送检细胞STR信息 送检细胞名: Jurkat E6.1 | 细胞库细胞STR信息 细胞库细胞名: Jurkat E6.1 | ||||||
| Allele1 | Allele2 | Allele3 | Allele4 | Allele1 | Allele2 | Allele3 | Allele4 | |
| Amelogenin | X | Y | X | Y | ||||
| CSF1PO | 10 | 11 | 12 | 13 | 10 | 11 | 12 | 13 |
| CSF1PO | 11 | 12 | 11 | 12 | ||||
| D2S1338 | 19 | 23 | 19 | 23 | ||||
| D3S1358 | 15 | 15 | ||||||
| D3S1358 | 15 | 17 | 15 | 17 | ||||
| D5S818 | 9 | 9 | ||||||
| D7S820 | 8 | 10 | 8 | 10 | ||||
| D7S820 | 8 | 12 | 8 | 12 | ||||
| D8S1179 | 12 | 13 | 14 | 15 | 12 | 13 | 14 | 15 |
| D8S1179 | 13 | 14 | 13 | 14 | ||||
| D13S317 | 8 | 12 | 8 | 12 | ||||
| D16S539 | 11 | 11 | ||||||
| D18S51 | 12 | 13 | 20 | 21 | 12 | 13 | 20 | 21 |
| D18S51 | 13 | 21 | 13 | 21 | ||||
| D19S433 | 14 | 15.2 | 14 | 15.2 | ||||
| D21S11 | 30.2 | 31.2 | 33.2 | 30.2 | 31.2 | 33.2 | ||
| D21S11 | 31.2 | 33.2 | 31.2 | 33.2 | ||||
| FGA | 20 | 21 | 20 | 21 | ||||
| Penta D | 11 | 13 | 11 | 13 | ||||
| Penta E | 10 | 12 | 10 | 12 | ||||
| TH01 | 6 | 9.3 | 6 | 9.3 | ||||
| TPOX | 8 | 10 | 8 | 10 | ||||
| vWA | 18 | 18 | ||||||
| vWA | 18 | 19 | 18 | 19 | ||||
* 该细胞系与收录于ATCC, DSMZ, JCRB 和 RIKEN数据库的细胞系STR数据匹配。
结论：该细胞 STR 鉴定正确。
结论：该细胞 STR 鉴定正确。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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