MAGEA4基因敲除A375细胞
货号:
EDJ-KQ18108
物种:
人
细胞名称:
A-375
基因名称:
MAGEA4
基因ID:
4103
规格:
1×10⁶cells
MAGEA4基因敲除细胞(A375)是由艾迪基因优化的CRISPR/Cas9系统编辑而成，采用Sanger测序法验证敲除，保证单克隆，活性良好。
| 货号 | EDJ-KQ18108 |
|---|---|
| 产品名称 | MAGEA4基因敲除A375细胞 |
| 细胞 | A375 |
| Cellosaurus ID | CVCL_0132 |
| 细胞别名 | A 375, A375, A375-MEL, A375-mel, A375mel, 375 |
| 基因 | MAGEA4 |
| 基因ID | |
| 基因别名 | CT1.4|MAGE-41|MAGE-X2|MAGE4|MAGE4A|MAGE4B |
| 摘要 |
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]
|
| 癌症类型 | Melanoma |
| 细胞形态 | 贴壁 |
| 传代比率 | 1/4-1/3,2 days |
| 完全培养基 | DMEM+10% FBS+1% GlutaMax |
| 冻存培养基 | 95% 完全培养基+5% DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
| Loci | 送检细胞STR信息 送检细胞名: A-375 | 细胞库细胞STR信息 细胞库细胞名: A-375 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 11 | 12 | 11 | 12 |
| D2S1338 | 16 | 24 | 16 | 24 |
| D3S1358 | 15 | 17 | 15 | 17 |
| D5S818 | 12 | 12 | ||
| D7S820 | 9 | 9 | ||
| D8S1179 | 11 | 14 | 11 | 14 |
| D13S317 | 11 | 14 | 11 | 14 |
| D16S539 | 9 | 9 | ||
| D18S51 | 12 | 17 | 12 | 17 |
| D19S433 | 13 | 14.2 | 13 | 14.2 |
| D21S11 | 29 | 30 | 29 | 30 |
| FGA | 23 | 23 | ||
| Penta D | 9 | 15 | 9 | 15 |
| Penta E | 10 | 12 | 10 | 12 |
| TH01 | 8 | 8 | ||
| TPOX | 8 | 10 | 8 | 10 |
| vWA | 16 | 17 | 16 | 17 |
| D6S1043 | 11 | 14 | ||
| D12S391 | 18 | 21 | 18 | 21 |
| D2S441 | 11 | 11 | ||
* 该细胞系与收录于ATCC, DSMZ, JCRB 和 RIKEN数据库的细胞系STR数据匹配。
结论：该细胞 STR 鉴定正确。
结论：该细胞 STR 鉴定正确。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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