MRE11（c.403-6G>A）点突变HAP1细胞
货号:
EDC03548
物种:
人
细胞名称:
HAP1
基因名称:
MRE11
基因ID:
4361
MRE11（c.403-6G>A）点突变HAP1细胞基于新开发的Bingo™平台，该平台采用优化升级版的Prime Editing (PE)基因点突变系统——目前最高效、最安全的技术。该平台可以实现精准、高效的基因点突变，从而获得高活性和稳定的细胞系。艾迪基因拥有大量的PE点突变细胞库存，能够高效、及时地提供高质量的产品。
| 货号 | EDC03548 |
|---|---|
| 产品名称 | MRE11（c.403-6G>A）点突变HAP1细胞 |
| 物种 | 人 |
| 细胞 | HAP1 |
| 突变位点 | c.403-6G>A |
| 细胞别名 | HAP-1 |
| 基因 | MRE11 |
| 基因ID | |
| 摘要 |
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
|
| 细胞形态 | 贴壁生长 |
| 传代比率 | 1:8~1:10 |
| 完全培养基 | IMDM+10%FBS |
| 冻存培养基 | 90%FBS+10%DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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