RAD51B（c.84+28T>G）点突变HAP1细胞
货号:
EDC03586
物种:
人
细胞名称:
HAP1
基因名称:
RAD51B
基因ID:
5890
RAD51B（c.84+28T>G）点突变HAP1细胞基于新开发的Bingo™平台，该平台采用优化升级版的Prime Editing (PE)基因点突变系统——目前最高效、最安全的技术。该平台可以实现精准、高效的基因点突变，从而获得高活性和稳定的细胞系。艾迪基因拥有大量的PE点突变细胞库存，能够高效、及时地提供高质量的产品。
| 货号 | EDC03586 |
|---|---|
| 产品名称 | RAD51B（c.84+28T>G）点突变HAP1细胞 |
| 物种 | 人 |
| 细胞 | HAP1 |
| 突变位点 | c.84+28T>G |
| 细胞别名 | HAP-1 |
| 基因 | RAD51B |
| 基因ID | |
| 摘要 |
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016]
|
| 细胞形态 | 贴壁生长 |
| 传代比率 | 1:8~1:10 |
| 完全培养基 | IMDM+10%FBS |
| 冻存培养基 | 90%FBS+10%DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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