XPC(c.2604+28C>G)点突变HAP1细胞
货号:
EDC03389
物种:
人
细胞名称:
HAP1
基因名称:
XPC
基因ID:
7508
XPC(c.2604+28C>G)点突变HAP1细胞基于新开发的Bingo™平台,该平台采用优化升级版的Prime Editing (PE)基因点突变系统——目前最高效、最安全的技术。该平台可以实现精准、高效的基因点突变,从而获得高活性和稳定的细胞系。艾迪基因拥有大量的PE点突变细胞库存,能够高效、及时地提供高质量的产品。
| 货号 | EDC03389 |
|---|---|
| 产品名称 | XPC(c.2604+28C>G)点突变HAP1细胞 |
| 物种 | 人 |
| 细胞 | HAP1 |
| 突变位点 | c.2604+28C>G |
| 细胞别名 | HAP-1 |
| 基因 | XPC |
| 基因ID | |
| 摘要 |
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
|
| 细胞形态 | 贴壁生长 |
| 传代比率 | 1:8~1:10 |
| 完全培养基 | IMDM+10%FBS |
| 冻存培养基 | 90%FBS+10%DMSO |
* 仅供科研使用,不适用于人体或动物,包括临床、治疗或诊断用途。
* 研究用途免责声明:本内容基于公开的研究数据、生物信息学资源及计算分析生成,仅供研究参考。