MSLN基因过表达K-562稳转细胞
货号:
EDC01466
物种:
人
细胞名称:
K-562
基因名称:
MSLN
基因ID:
10232
规格:
1×10⁶cells
艾迪基因基于自身成熟的基因编辑平台，通过慢病毒或转座子递送系统，将MSLN基因整合至K-562细胞的基因组中，然后经过真核抗性标记筛选出阳性细胞池，再使用3D单细胞打印技术挑选单克隆细胞，最后经过表达水平验证，检测合格后对细胞进行扩增和冻存。
| 货号 | EDC01466 |
|---|---|
| 产品名称 | MSLN基因过表达K-562稳转细胞 |
| Cellosaurus ID | CVCL_U226 |
| 细胞别名 | K562, K.562, K 562, KO, GM05372, GM05372E |
| 基因 | MSLN |
| 基因别名 | MPF|SMRP |
| 摘要 |
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
|
| 癌症类型 | Chronic Myelogenous Leukemia |
| 细胞形态 | 成淋巴细胞样，悬浮生长 |
| 传代比率 | 1/3，2days |
| 完全培养基 | 1640+10%FBS |
| 冻存培养基 | 95%完全培养基+5%DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
| Loci | 送检细胞STR信息 送检细胞名: K-562 | 细胞库细胞STR信息 细胞库细胞名: K-562 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1P0 | 9 | 10 | 9 | 10 |
| D2S1338 | 17 | 17 | ||
| D3S1358 | 16 | 16 | ||
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 9 | 11 | 9 | 11 |
| D8S1179 | 12 | 12 | ||
| D13S317 | 8 | 8 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 15 | 16 | 15 | 16 |
| D19S433 | 14 | 14.2 | 14 | 14.2 |
| D21S11 | 29 | 31 | 29 | 31 |
| FGA | 21 | 24 | 21 | 24 |
| Penta D | 9 | 13 | 9 | 13 |
| Penta E | 5 | 14 | 5 | 14 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 16 | 16 | ||
| D6S1043 | 11 | |||
| D12S391 | 23 | 23 | ||
| D2S441 | 10 | 14 | 10 | 14 |
* 该细胞系与收录于ATCC, DSMZ, JCRB 和 RIKEN数据库的细胞系STR数据匹配。
结论：该细胞 STR 鉴定正确。
结论：该细胞 STR 鉴定正确。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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