LentiGuide-ROCK1-sgRNA3-PURO

艾迪基因承诺所提供的质粒载体经过严格质检与验证,保证无内毒素、经项目验证质粒载体可达到预期实验目的。  更多

货号 : EDV1278-S885

价格:   咨询价格

数量

艾迪基因承诺所提供的质粒载体经过严格质检与验证,保证无内毒素、经项目验证质粒载体可达到预期实验目的。
质粒抗性 Amp
细胞筛选抗性 Puro
摘要
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]
* 仅供科研使用,不适用于人体或动物,包括临床、治疗或诊断用途。

图谱

储存条件

质粒短期保存温度为-20℃,长期保存温度为-80℃。

* 研究用途免责声明:本内容基于公开的研究数据、生物信息学资源及计算分析生成,仅供研究参考。
联系我们
*
*
*
来源:
✖ service online

  • 留言
  • You can send email to contact us.
    邮箱
  • You can send email to contact us.
    电话
    联系电话
    中国总部
    18102225074(微信同号)

  •  回到顶部