艾迪基因承诺所提供的质粒载体经过严格质检与验证,保证无内毒素、经项目验证质粒载体可达到预期实验目的。
| 质粒抗性 | Amp |
|---|---|
| 细胞筛选抗性 | Puro |
| 摘要 |
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
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* 仅供科研使用,不适用于人体或动物,包括临床、治疗或诊断用途。
图谱
储存条件
质粒短期保存温度为-20℃,长期保存温度为-80℃。
* 研究用途免责声明:本内容基于公开的研究数据、生物信息学资源及计算分析生成,仅供研究参考。