艾迪基因承诺所提供的质粒载体经过严格质检与验证，保证无内毒素、经项目验证质粒载体可达到预期实验目的。
| 质粒抗性 | Amp |
|---|---|
| 细胞筛选抗性 | Puro |
| 摘要 |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
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* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
图谱
储存条件
质粒短期保存温度为-20℃，长期保存温度为-80℃。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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