lentiCRISPR v3-TLR2-sgRNA1-PURO

艾迪基因承诺所提供的质粒载体经过严格质检与验证,保证无内毒素、经项目验证质粒载体可达到预期实验目的。  更多

货号 : EDV1140-S747

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数量

艾迪基因承诺所提供的质粒载体经过严格质检与验证,保证无内毒素、经项目验证质粒载体可达到预期实验目的。
质粒抗性 Amp
细胞筛选抗性 Puro
摘要
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
* 仅供科研使用,不适用于人体或动物,包括临床、治疗或诊断用途。

图谱

储存条件

质粒短期保存温度为-20℃,长期保存温度为-80℃。

* 研究用途免责声明:本内容基于公开的研究数据、生物信息学资源及计算分析生成,仅供研究参考。
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