说明书 
B2M基因敲除细胞(A375)是由艾迪基因优化的CRISPR/Cas9系统编辑而成，采用Sanger测序法验证敲除，保证单克隆，活性良好。
| 货号 | EDC07626 |
|---|---|
| 产品名称 | B2M基因敲除A375细胞 |
| 细胞 | A375 |
| Cellosaurus ID | CVCL_0132 |
| 细胞别名 | A 375, A375, A375-MEL, A375-mel, A375mel, 375 |
| 基因 | B2M |
| 基因ID | |
| 基因别名 | AMYLD6|IMD43|MHC1D4 |
| 摘要 |
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
|
| 癌症类型 | Melanoma |
| 细胞形态 | 贴壁 |
| 传代比率 | 1/4-1/3,2 days |
| 完全培养基 | DMEM+10% FBS+1% GlutaMax |
| 冻存培养基 | 95% 完全培养基+5% DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
| Loci | 送检细胞STR信息 送检细胞名: A-375 | 细胞库细胞STR信息 细胞库细胞名: A-375 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 11 | 12 | 11 | 12 |
| D2S1338 | 16 | 24 | 16 | 24 |
| D3S1358 | 15 | 17 | 15 | 17 |
| D5S818 | 12 | 12 | ||
| D7S820 | 9 | 9 | ||
| D8S1179 | 11 | 14 | 11 | 14 |
| D13S317 | 11 | 14 | 11 | 14 |
| D16S539 | 9 | 9 | ||
| D18S51 | 12 | 17 | 12 | 17 |
| D19S433 | 13 | 14.2 | 13 | 14.2 |
| D21S11 | 29 | 30 | 29 | 30 |
| FGA | 23 | 23 | ||
| Penta D | 9 | 15 | 9 | 15 |
| Penta E | 10 | 12 | 10 | 12 |
| TH01 | 8 | 8 | ||
| TPOX | 8 | 10 | 8 | 10 |
| vWA | 16 | 17 | 16 | 17 |
| D6S1043 | 11 | 14 | ||
| D12S391 | 18 | 21 | 18 | 21 |
| D2S441 | 11 | 11 | ||
* 该细胞系与收录于ATCC, DSMZ, JCRB 和 RIKEN数据库的细胞系STR数据匹配。
结论：该细胞 STR 鉴定正确。
结论：该细胞 STR 鉴定正确。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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