KDR(c.3405-92A>G)点突变HAP1细胞
货号:
EDC03520
物种:
人
细胞名称:
HAP1
基因名称:
KDR
基因ID:
3791
KDR(c.3405-92A>G)点突变HAP1细胞基于新开发的Bingo™平台,该平台采用优化升级版的Prime Editing (PE)基因点突变系统——目前最高效、最安全的技术。该平台可以实现精准、高效的基因点突变,从而获得高活性和稳定的细胞系。艾迪基因拥有大量的PE点突变细胞库存,能够高效、及时地提供高质量的产品。
| 货号 | EDC03520 |
|---|---|
| 产品名称 | KDR(c.3405-92A>G)点突变HAP1细胞 |
| 物种 | 人 |
| 细胞 | HAP1 |
| 突变位点 | c.3405-92A>G |
| 细胞别名 | HAP-1 |
| 基因 | KDR |
| 基因ID | |
| 摘要 |
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
|
| 细胞形态 | 贴壁生长 |
| 传代比率 | 1:8~1:10 |
| 完全培养基 | IMDM+10%FBS |
| 冻存培养基 | 90%FBS+10%DMSO |
* 仅供科研使用,不适用于人体或动物,包括临床、治疗或诊断用途。
* 研究用途免责声明:本内容基于公开的研究数据、生物信息学资源及计算分析生成,仅供研究参考。