说明书 
MAPK7（p.D200A）点突变Ishikawa细胞基于新开发的Bingo™平台，该平台采用优化升级版的Prime Editing (PE)基因点突变系统——目前最高效、最安全的技术。该平台可以实现精准、高效的基因点突变，从而获得高活性和稳定的细胞系。艾迪基因拥有大量的PE点突变细胞库存，能够高效、及时地提供高质量的产品。
| 货号 | EDC07573 |
|---|---|
| 产品名称 | MAPK7（p.D200A）点突变Ishikawa细胞 |
| 物种 | 人 |
| 细胞 | Ishikawa |
| Cellosaurus ID | CVCL_2529 |
| 突变位点 | p.D200A |
| 细胞别名 | ISHIKAWA, ISHI |
| 基因 | MAPK7 |
| 基因ID | |
| 摘要 |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
|
| 癌症类型 | Endometrial Carcinoma |
| 传代比率 | 1:3~1:4 |
| 完全培养基 | DMEM+10%FBS |
| 冻存培养基 | 55% 基础培养基+40% FBS+5% DMSO |
* 仅供科研使用，不适用于人体或动物，包括临床、治疗或诊断用途。
| Loci | 送检细胞STR信息 送检细胞名: Ishikawa | 细胞库细胞STR信息 细胞库细胞名: Ishikawa | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | X | |
| CSF1PO | 12 | 13 | 11 | 12 |
| D2S1338 | 19 | 21 | 20 | |
| D3S1358 | 16 | 15 | 17 | |
| D5S818 | 10 | 11 | 10 | 11 |
| FGA | 21 | 23 | 21 | |
| TH01 | 9 | 10 | 9 | 10 |
| TPOX | 8 | 8 | ||
* 该细胞系与收录于ATCC, DSMZ, JCRB 和 RIKEN数据库的细胞系STR数据匹配。
结论：该细胞 STR 鉴定正确。
结论：该细胞 STR 鉴定正确。
* 研究用途免责声明：本内容基于公开的研究数据、生物信息学资源及计算分析生成，仅供研究参考。
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